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In the consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE), GLP-1 RA is recommended as monotherapy in individuals with HbA1c 1% and weight reduction 3% e Compared to placebo f Compared to other incretin mimetics g Compared to exenatide and liraglutide h Compared to other therapies i Compared to comparator drugs j Compared to exenatide formulations and albiglutide Body Weight and Composition GLP-1 RA decreases gastrointestinal motility and hence increases the time for nutrient absorption

Many patients experience reduced cravings and steady weight loss over time

A 2023 study out of the University of British Columbia linked GLP-1 agonists to a heightened risk of severe gastrointestinal problems. These problems include gastroparesis, pancreatitis, and bowel obstruction
The differences between GLP-1 drugs include: Dosages
