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Common pathophysiological features exist between T2DM, AD, and PD, including oxidative stress, inflammation, insulin resistance, abnormal protein processing, and cognitive decline, and suggest that effective drugs for T2DM that positively impact the gutbrain axis could provide an effective treatment option for neurodegenerative diseases

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The patients Ive seen do best are those that have a solid foundation of lifestyle practices

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Estrogens upregulate PDGF expression and downregulate EGF expression in UFs (Yin et al., 2011)

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In vivo, owing to DPP-4 intervention, GLP-1s biological half-life is just 1 to 2 minutes

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