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Contrave (bupropion/naltrexone) is FDA-approved for chronic weight management in adults with obesity, or overweight and a weight-related health condition

The difference between the two dosages and the rates of NAION may indicate a dose dependent increase in risk of NAION. Benjamin Bert, MD Future research should focus on this potential dose-dependent increase in adverse events with the GLP-1 medications, Bert continued

With such heavy societal burdens, obesity and related chronic diseases have become major public health concerns in China and around the world