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The beneficial effects of [D-Ala 2 ]GIP to decrease synaptic loss and inflammation are preserved in 19 month old APP/PS1 mice [1070], suggesting that GIPR agonism may be beneficial even in more advanced stages of the disease

Weight loss decreases self-reported appetite and alters food preferences in overweight and obese adults: observational data from the DiOGenes study

If intolerable, discontinue and try an alternative (different GLP-1, older medication like phentermine, or non-medication approaches)

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