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Opened pens that are in use can be kept in the refrigerator or in a cool space between 59 degrees F and 86 degrees F, according to manufacturer guidelines
Thats why its a good idea to only bring the amount of doses youll need during your vacation (plus one extra in case your return flight gets delayed)
Oxidation of the hydrazide is most efficient in water under acidic conditions, whereas the actual cyclization step proceeds optimally in an organic solvent at neutral pH
