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Freedman DS, Butte NF, Taveras EM, Lundeen EA, Blanck HM, Goodman AB, et al

It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

It could aid individuals with obesity or associated health issues

The increase in Ca 2+ is mediated by IP3 induced release of intracellular Ca 2+ and by depolarization leading to activation of voltage dependent Ca 2+ channels