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Fifth, although the TriNetX US Collaborative Network includes data from multiple healthcare systems and a large, diverse patient population, the findings may not be fully generalizable to populations outside the United States or to healthcare settings with different prescribing practices, genetic backgrounds, or access to dermatologic care

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Where Standard Dosing Begins In large randomized clinical trials, GLP-1 therapy begins at defined initiation thresholds before gradual titration upward
