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The enzyme dipeptidyl peptidase 4 (DPP-IV) cleaves it between the second and third residues which renders it inactive within several minutes, and explains why GLP-1 cannot be used as a drug itself

The Phoenix metro area now hosts dozens of providers offering peptide therapy , ranging from specialized hormone optimization centers to general wellness spas that added peptides to their menu last month

4 Related Stories Weight loss medications show promise in preventing obesity-related cancers Single DNA injection provides long-lasting weight loss in mouse study Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations Non-peptidic small-molecule GLP-1R agonists, such as orforglipron, and other investigational agents are intrinsically resistant to proteolysis and do not require permeation enhancers or fasting administration