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Questions that were rare even five years ago now surface at nearly every follow-up visit especially among patients who continue to struggle with inflammation, persistent bloating, metabolic syndrome , or weight-related hormonal changes , and in those who feel under-treated or unresponsive to standard medical therapy

doi: 10.1136/gut.2005.069088

This suggests that GLP-1 drugs exert direct, independent physiological effects on the cardiovascular system that are not yet fully understood

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