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But the level of obesity in the US is absolutely a public health crisis, presents massive costs on both a personal and societal level and in large part seems to perpetuate as a disease state (Metabolic Syndrome etc) - its completely reasonable to think that modern science can cure this condition which is largely a symptom of modern lifestyles anyway

doi: 10.1210/endo.135.2.8033807

This is a recognised class effect that can reduce the absorption rate of certain oral medicines including oral contraceptives and drugs with a narrow therapeutic index and should be considered in any clinical or research setting

In some areas, its clear that GLP-1s have clearly strong, positive effects on an individuals health and well-being (i.e., diabetes, obesity), and in other areas, its not yet clear, but we may soon find the same (i.e., neurological diseases)