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For example, some gut microbes produce short-chain fatty acids that have been shown to stimulate GLP-1 release in experimental models
Increases in amylase and lipase levels were also observed but were asymptomatic, with one exception: a single case of acute pancreatitis that was classified as a serious adverse event
Strategy 2: Fermentable Fiber for SCFA Production The Science: L-cells express receptors for short-chain fatty acids (SCFAs)particularly butyrate and propionate
J Clin Endocrinol Metab (2003) 88:240411
