when did glp 1 agonists come out Evolution of GLP‐1 Receptor for Diabetes Treatment GLP-1 Agonists in Cardiovascular Diseases:

The authors compared changes in glycemic control and BMD with and without conversion from DPP-4 inhibitor to GLP-1 receptor agonist for 3 years and observed that patients who switched to the latter had greater decline in lumbar BMD than controls regardless of weight loss [12, 61]

One practical tip that comes directly from clinical guidance is to eat your protein first at each meal, before vegetables and carbs

Weight loss may be slow initially, and you usually see the benefits a few weeks after being on these medications when your dose is increased

Semaglutide and the risk of diabetic retinopathy-current perspective