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PMID 20727946
Overall, theoretically, differences in the pharmacokinetic profiles of different GLP-1RAs may have important implications for their efficacy in BAD and perhaps help explain why liraglutide could be superior in reducing symptoms of BAD as compared with the more potent and longer-acting semaglutide
Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases
den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, Bakker BM
