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A key limitation of preclinical research, including GLP-1RA studies, is that most experiments are conducted in male animals
Similar content being viewed by others Introduction Diet and exercise have been the cornerstones of obesity treatment since the time of Hippocrates, with additional therapies including laxatives, purgatives, and diuretics [1]
Physiologic stress can contribute to hyperglycemia in patients with diabetes
It simultaneously activates both receptor pathways, producing additive effects on insulin secretion, glucagon suppression, and appetite regulation that exceed what GLP-1 agonism alone achieves
