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However, advances in biomedical science have revealed that physiological systems function through highly interconnected networks

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Pathological protein aggregation is a unifying hallmark of NDDs: A and tau in AD, -synuclein in PD and MSA, mutant huntingtin in HD, and TDP-43 in ALS

The FDA label specifically warns about the risk of cholelithiasis, noting that substantial or rapid weight loss itself is an established risk factor for gallstone formation
