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Patients also reported sustained appetite controlthe hallmark of successful long-term weight managementrather than the appetite rebound some experience with short-term diets
39 In the SURMOUNT-1 and SURMOUNT-3 trials, the weight loss ranged between 15% and nearly 21% after 72 weeks of treatment

Cost-effectiveness analysis of semaglutide 2.4 mg for the treatment of adult patients with overweight and obesity in the United States
Oral analgesics: For significant discomfort, acetaminophen (500-1000 mg every 6 hours as needed, not exceeding 3000 mg daily) can provide pain relief