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While this medication has demonstrated significant benefits for glycemic control and weight reduction, it carries a boxed warningthe FDA's most serious safety alertregarding thyroid C-cell tumors observed in animal studies

Pharmacologically mediated, marked initial maternal body weight loss and reductions in body weight gain and food consumption coincided with the occurrence of sporadic abnormalities (vertebra, sternebra, ribs) at 0.075 mg/kg twice weekly (3X human exposure)

The safer approach is to wait at least two to four weeks after completing antibiotics before starting Pendulum

Weghuber, D., et al
