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Description
Although topiramates pharmacodynamic profile overlaps with older carbonic-anhydrase inhibitors such as acetazolamide, it differs by exhibiting negligible effects on systemic pH at doses below 100 mg per day
Weeks 5 through 8: 3 to 5mg daily
At Week 72, mean bodyweight reduction was significantly greater with tirzepatide (16.1% for 10 mg and 21.1% for 15 mg) compared to placebo ( p 1)
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