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GLP-1 receptors have been found in both healthy and OA-affected cartilage cells in rat knees

Also from other studies using other GLP-1 analogs, we expected rather decreased than increased dopamine levels after semaglutide (Egecioglu et al., 2013a, 2013b Fortin and Roitman, 2017
Patients randomized to exenatide started on a dose of 5 mcg twice-daily for 4 weeks and then were escalated to 10 mcg twice daily

Studies have indicated that semaglutide can reduce the risk of major cardiovascular events, such as heart attacks and strokes, in patients with type 2 diabetes
