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Description
Int J Womens Health

These bispecific molecules that antagonize GIPR and agonize GLP-1R pathways led to decreases in BW and improvements in metabolic parameters in obese mice and monkeys 34

Currently, the safety and efficacy in special populations, such as children, pregnant women, and older adults, remain unclear, requiring further studies

Weight Regain After Discontinuation Is the Rule, Not the Exception Without addressing: Insulin sensitivity Muscle preservation Nutrient status Lifestyle structure Most patients experience partial or full weight regain after stopping GLP-1 therapy
