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What the Research Shows This warning exists because, during early laboratory trials, researchers found that semaglutide caused thyroid C-cell tumours in rats and mice
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Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography

As semaglutide can cause nutritional deficiencies such as vitamin B12 deficiency, many clinicians believe that maintaining optimal B12 levels can reduce fatigue, improve tolerance, and promote overall health during semaglutide therapy