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In the case of liraglutide, research demonstrated enhanced endothelial function via stimulation of the mammalian target of rapamycin complex 2/protein kinase B (mTORC2)/Akt pathway, resulting in increased NO production, elevated telomerase activity, and anti-apoptotic effects [115]

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We have recently generated a transgenic mouse line that allows for tissue-selective expression of the endogenous Gcg gene [9]

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