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First of all, the trial was called STEP, and it was a global trial of about 2000 individuals in the step one trial in which individuals, all of them who were overweight or had obesity, many with a medical problem, were randomized blindly to either take this new drug

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doi: 10.1111/obr.13535

Notably, retatrutide trials showed an overwhelming clearance of liver fat, with some cohorts experiencing up to an 80% reduction in hepatic lipid content, presenting a massive benefit for individuals dealing with metabolic dysfunction-associated steatotic liver disease (MASLD)