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As a result, the low DGAT1 expression observed in the presence of Ex-4 is most likely a response to reduced FAs uptake rather than reduced de novo lipogenesis, ruling out a role for reduced de novo lipogenesis in the Ex-4-induced steatosis improvement

In this regard, Fgf21 mRNA levels were upregulated in eWAT and iWAT from FGF21 Alb-KO mice at 72 h of G49 treatment (Fig

Students t test and Fischer exact test were used to compare type 2 diabetes vs NGT, and paired t tests were used to compare pre vs post metformin

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