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Nicotinamide phosphoribosyltransferase (NAMPT)-mediated nicotinamide adenine dinucleotide (NAD + ) biosynthesis in major metabolic organs such as the liver, adipose tissue, and skeletal muscle plays a crucial role in obesity- and aging-associated organ derangements

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For those who used an alternative as-treated definition for drug use, the analysis found a median follow-up time of 1.8 years with 90-day gap and tail periods (HR, 1.37