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The primary concerns with using discoloured tirzepatide include: Loss of therapeutic effect : Degradation of the active peptide may render the medication ineffective, leading to inadequate glycaemic control or failure to achieve intended weight management outcomes Potential toxicity : Degradation products or contaminants responsible for the colour change may pose direct health risks Immunogenicity : Altered protein structures can potentially trigger unwanted immune responses Infection risk : If discolouration results from contamination, injection could introduce harmful substances into subcutaneous tissue If you discover discoloured tirzepatide, you should: If you have inadvertently used discoloured tirzepatide and experience symptoms of a severe allergic reaction (such as difficulty breathing, swelling of face/throat, or severe rash), call 999 or go to A&E immediately

No serious cardiovascular events have been attributed to retatrutide in published trials

Plain compounded tirzepatide without additives is also available

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