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23: CMC issues tripped up Venatorx Pharmaceuticals and Melinta Therapeutics in their quest to gain FDA approval for the urinary tract infection antibiotic cefepime-taniborbactam
Consequently, the current study indicates that the degradation rate of GLP-1 differs across species, and that accurate estimation of GLP-1 secretion in rodents (particularly in mice) requires assays that can cope with this
For those who want to be conservative, 30 days provides additional clearance buffer
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