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The first GLP-1 analog was approved for the treatment of type 2 diabetes in 2005 Trusted Source PubMed Central Go to source

The growth of mass-produced compounded products raises serious patient safety concerns

By examining how these agents interact with key nodes of the reward circuitryparticularly within the mesocorticolimbic dopamine systemwe aim to elucidate the mechanisms through which GLP-1 signaling may attenuate drug-seeking behavior, reduce relapse vulnerability, and modulate craving