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One of the biggest differences between the two medications is how they're taken, says Deborah Horn, DO, director of obesity medicine at UTHealth Houston

Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes

Semaglutide reduced MACE by 20% compared to placebo over a median follow-up of 33 months

The key question becomes whether the records support a link to one product, multiple products, or another cause, especially when symptoms overlap across drugs in the same class
