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Estrogen therapy, alone or combined with progestin, is commonly prescribed for managing these menopausal symptoms

While we have not tested the full combination in females, we have tested GDF8 and ActA blockade in lean female monkeys 28 and in postmenopausal women in our Phase 1 clinical study in the accompanying manuscript (Gonzalez Trotter et al

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The metabolism of lipids starts with the breakdown of ingested fats into smaller particles by bile, followed by the conversion into free fatty acids and monoglycerides by enzymes from the pancreas and small intestine [19] (Fig
