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In October, Lilly reported that the oral therapy orforglipron bested AstraZenecas Farxiga in a Phase III diabetes trial

However, the potential risk of side effects may outweigh the benefits, and no studies support the combination of the two

Most gastrointestinal adverse events were mild or moderate in nature, and no grade 4 or grade 5 gastrointestinal adverse events were observed
The company said the change aims to reduce access barriers, especially for patients whose out-of-pocket costs are tied to the list price
