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Larger and longer studies in broader populations are needed to fully understand the safety and efficacy in people with alcohol use disorder, but these initial findings are promising. In the research, published in the journal JAMA Psychiatry, 48 people with drinking problems were recruited, who had not been actively seeking treatment

Ophthalmology 127 , 15071514 (2020)

Starting with lower doses and gradually increasing helps minimize digestive upset, and most side effects improve within weeks as your body adjusts

The STEP trials tracked semaglutide safety for up to 68 weeks, with safety profiles remaining stable throughout the study period