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32 Patient adherence to calorie restriction often wanes over time and many patients experience cycles of weight loss and gain

Recently, the Food and Drug Administration (FDA) approved the use of some GLP-1 agonists for promoting weight loss in people with obesity

Davies said weight loss of up to 5% can improve hyperglycemia and hypertension, 5% to 10% weight loss can prevent type 2 diabetes and improve polycystic ovary syndrome and dyslipidemia, 10% to 15% weight loss can lead to improvements in cardiovascular disease and 15% or greater weight loss may induce type 2 diabetes remission and lower risks for CV mortality and heart failure with preserved ejection fraction

K., Brenhouse H
