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Here are the top side effects to pay attention to: GI symptoms

Evidence suggests that GLP-1s are not only effective in preventing the accumulation of amyloid beta, a protein commonly associated with Alzheimer's, but also in mitigating the hyperphosphorylation and aggregation of tau, another critical protein in the disease's progression
Devices delivering drugs require device certification and additional marketing authorisation for the pharmacological component [113]

2022 for retatrutide, Carmona et al