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The primary efficacy parameter was mean percent change in BMI from baseline after 52 weeks on a therapeutic regimen of setmelanotide compared to placebo

This extended fullness sensation after eating helps prevent overeating and reduces the urge to snack between meals

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Bonde L, Vilsbll T, Nielsen T, Bagger JI, Svare JA, Holst JJ, Larsen S, Knop FK