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Tirzepatide has a slightly higher molecular weight, which theoretically makes it even less likely to transfer into milk, but both appear similarly safe based on available studies

26 It is also feasible that reduction in AMD risk factors such as obesity, cardiovascular disease, and hyperlipidemia with GLP-1RAs could further provide benefit by reducing systemic inflammation and vascular risk factors
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doi: 10.1016/j.jff.2016.12.006 203 MahlujiSOstadrahimiAMobasseriMEbrahimzade AttariVPayahooL

Healthcare professionals and patients should be extremely cautious before prescribing or using these medications, and focus on safe, evidence-based dietary and lifestyle strategies for weight loss and metabolic health as first, second, and third-line treatment
