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The prevention of the glucagon release helps prevent the liver from producing excess glucose, which spikes the blood sugar levels

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The FDA has a tool that can help you determine how many you need based on age, gender, and activity level

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This analysis found that canagliflozin 300 mg was associated with the lowest cost per 1% reduction in HbA1c at all three points in the diabetes treatment pathway, though differences in cost-effectiveness between the SGLT-2 inhibitors were small

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Management: Safe to combine

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