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Description
The prevention of the glucagon release helps prevent the liver from producing excess glucose, which spikes the blood sugar levels

The FDA has a tool that can help you determine how many you need based on age, gender, and activity level

This analysis found that canagliflozin 300 mg was associated with the lowest cost per 1% reduction in HbA1c at all three points in the diabetes treatment pathway, though differences in cost-effectiveness between the SGLT-2 inhibitors were small

Management: Safe to combine
