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As with other areas of research, subtyping studies have primarily been conducted using samples from populations with limited diversity (Higginbotham et al., 2023) and have focused on AD

The two agents may be started simultaneously or sequentially , depending on clinical circumstances and patient factors

Most patients who experience insomnia report symptoms that peak during weeks 1-4 and gradually diminish as their body adjusts

Additional research with rigorous study design is needed to clarify these relationships
