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5 In accordance with medical guidelines, Semaglutide for weight loss is intended to be used alongside a reduced-calorie diet and increased physical activity

Wegovy contains semaglutide and is approved specifically for weight management in the New Zealand (16), while Mounjaro acts on two hormone pathways (GLP-1 and GIP) and has demonstrated greater average weight loss in head-to-head clinical trials (17)

Smaller observational studies suggest semaglutide may be tolerated with careful insulin adjustment, but safety requires close physician supervision and regular blood glucose monitoring