uti and tirzepatide Burning Questions About UTIs? Addressing Urinary Tract Infections Does Rybelsus Cause UTI? Evidence

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Kadowaki T, Chin R, Ozeki A, Imaoka T, Ogawa Y (2022) Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): a multicentre, randomised, open-label, parallel-group, phase 3 trial

All three medications belong to the GLP-1 receptor agonist class but have some key differences: Mounjaro (Tirzepatide): Mechanism: Dual GIP and GLP-1 receptor agonist Administration: Once-weekly injection Average Weight Loss: Up to 22.5% of body weight in 72 weeks [1] Primary Indication: Type 2 diabetes (weight loss indication pending) Price at Great North Pharmacy: Starting at $158.99 per vial [2] Ozempic (Semaglutide): Mechanism: GLP-1 receptor agonist Administration: Once-weekly injection Average Weight Loss: Up to 15% of body weight in 68 weeks [6] Primary Indication: Type 2 diabetes (approved for weight loss under brand name Wegovy) Price at Great North Pharmacy: Starting at $429.97 for 1 pen [2] Saxenda (Liraglutide): Mechanism: GLP-1 receptor agonist Administration: Daily injection Average Weight Loss: Up to 8% of body weight in 56 weeks [7] Primary Indication: Chronic weight management Price at Great North Pharmacy: Starting at $515 for 5 pens [2] Effectiveness: Clinical trials suggest that Mounjaro may lead to greater weight loss compared to both Ozempic and Saxenda