glp-1 receptor agonists as Treatments for Type 2 Diabetes Possible mechanisms of action of
Description
NaB-enhanced hepatic GLP-1R expression via inhibiting HDAC It has been reported that short-chain fatty acids (SCFAs) including NaB are able to regulate the immune response and metabolism through the activation of GPRs, such as GRP43 and GRP109a or through the inhibition of HDAC 27,28
Due to the retrospective nature of the data, other confounding factors may have affected the results as well
This approach may reduce gastrointestinal side effects by up to 70%, improve medication tolerability, and lower monthly costs
The cost of the 9-mg and 25-mg doses is $299 per month, which is $50 cheaper than the injections
