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The deeper lesson: in any consumer-category disruption, the brands with sophisticated reputation infrastructure and crisis-communications discipline respond within months
In respect to their cardiovascular effects among patients with T2DM, both GLP-1RAs and SGLT2is have been shown to reduce the risk of MACE (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke), with GLP-1RAs reducing the risk of non-fatal stroke to a greater extent [3, 6]

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In this article we review the most relevant data exploring the mechanisms involved in the effects of GLP-1RAs in the brainadipocyte axis