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Genetic analyses linked BMI-related GLP-1 receptor activation to better mental well-being and lower odds of major depressive disorder and bipolar disorder
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However, gastrointestinal side effects related to GLP-1 RA need appropriate clinical management to mitigate risks and maximize the benefits of therapy in people with IBD
Where the field goes next The EVOKE/EVOKE+ results reinforce that singlemechanism interventions may not be sufficient to modify Alzheimers course in symptomatic stages
