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While treatment strategies for AD have principally targeted individual pathological hallmarks such as amyloid and tau with limited success in modifying the disease course, to have an effective disease-modifying treatment it may be necessary to target multiple pathologies [8, 9]

For example, if the main issue for the patient is postprandial hyperglycemia, and fasting glucoses are near normal, an agent, such as nateglinide, that has a limited effect on the fasting glucose would be ideal

It's even bigger than opioids," said Leggio, referring to the addiction crisis that began with pain pills and morphed into people taking illicit fentanyl

Indications/contraindications Who can take it: Patients with obesity or excess weight with a Body Mass Index (BMI) of 30 or higher