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Frias JP, Nauck MA, Van J, Benson C, Bray R, Cui X, et al

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Because this formula contains 5-HTP, a direct serotonin precursor, and berberine, which inhibits CYP enzymes that process many antidepressants, there is a documented interaction concern with SSRIs, SNRIs, MAOIs, and serotonergic medications

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