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Glucagon-like peptide-1 (GLP-1) agonists are injectable therapies that exploit endogenous hormonal blood glucose control for people with diabetes

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While this persistence rate is a marked improvement over the 10% observed for obesity-indicated GLP-1s, it still leaves 76% of potential demand unrealized

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This is a multifunctional receptor with a crucial role in the feeding state response, able to regulate glucose and lipid metabolism, bile acid homeostasis, and liver regeneration [116]

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Its taken as a once-weekly injection and is approved for both type 2 diabetes and weight management

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