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Description
While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives
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Triple agonist retatrutide yielded 28.7% weight loss at 68 weeks, besting Zepbounds Phase III data, while also showing benefit in knee osteoarthritis pain.
