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Possible concerns for older adults include: loss of bone or muscle mass (or both) if weight loss is too rapid or not paired with resistance exercise (also called strength training) nutrient deficiencies if their appetite decreases without balancing nutrition, which can worsen existing vitamin B12, vitamin D, and protein deficiencies dehydration, dizziness, or digestive system side effects (such as diarrhea), which may cause new or worsened health problems hypoglycemia (low blood sugar) or hypotension (low blood pressure), which can affect people already taking medications for these conditions increased heart rate or increased blood pressure, which may carry a higher risk in older adults who have heart disease or take heart medications Glucagon-like peptide-1 (GLP-1) receptor agonists are prescription drugs used for weight management and other conditions