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Similarly, studies have shown that GLP-1-based therapeutics can delay the progression of kidney disease in individuals with Type 2 diabetes, although the mechanisms are not well understood
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In an attempt to develop a strategy to prolong the physiological t1/2 and enhance the potency of GLP-1, a fusion protein consisting of active human GLP-1 and mouse IgG1 heavy chain constant regions (GLP-1/Fc) was generated
