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In recent years, this type of drug, known as a GLP-1 agonist has proven effective in diabetic control
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Here authors report the cryo-EM structure of GLP-1R bound to an ago-allosteric modulator in complex with heterotrimeric Gs which offers insights into the molecular details of ago-allosterism.
From delayed gastric emptying to gastroparesis, experts discuss how semaglutide affects the gut and what to know about its side effects
